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 DNA replication of the leading and lagging strand The helicase unzips the double-stranded DNA for replication, making a forked structure. The primase generates short strands of RNA that bind to the single-stranded DNA to initiate DNA synthesis by the DNA polymerase. This enzyme can work only in the 5' to 3' direction, so it replicates the leading strand continuously. Lagging-strand replication is discontinuous, with short Okazaki fragments being formed and later linked together. This image is linked to the following Scitable pages:
The decoding of information in a cell's DNA into proteins begins with a complex interaction of nucleic acids. Learn how this step inside the nucleus leads to protein synthesis in the cytoplasm.
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Register now for special offers +91 Home > English > Class 12 > Biology > Chapter > Sample Paper 2022 > The main reason for the presen... Video Solution: The main reason for the presence of both a leading and a lagging strand during DNA replication is, UPLOAD PHOTO AND GET THE ANSWER NOW! Text Solution DNA polymerase can read and synthesize only in the direction of 3'-to-5'DNA polymerase can only synthesize one strand at a timeOnly one strand is available to be read at any given timeThere are not enough RNA primers to have both strands be synthesized simultaneously Answer Step by step video solution for [object Object] by Biology experts to help you in doubts & scoring excellent marks in Class 12 exams. Question Details till 29/09/2022
Related Biology VideosShow More Add a public comment... Follow Us: Popular Chapters by Class: If you're seeing this message, it means we're having trouble loading external resources on our website. If you're behind a web filter, please make sure that the domains *.kastatic.org and *.kasandbox.org are unblocked. The double stranded DNA is first unzipped by an enzyme called helicase. Helicase separates the two strands of DNA, and creates the replication fork. Essentialy two single stranded DNA chains are created, both facing different directions. On the leading strand, an RNA primer is created by RNA ploymerase and DNA polymerase III will continously build that strand, since it is building the DNA chain in the same direction as helicase unzips the DNA. On the lagging strand, the DNA plymerase moves the opposite direction as helicase, thus it can only copy a small length of DNA at one time. Because of the different directions the two enzymes moves on the lagging strand, the DNA chain is only synthetised in small fragments. Hence it is called the lagging strand. Why is there both a leading and a lagging strand in DNA replication?Why must there be a lagging strand during DNA synthesis? Explanation: The lagging strand exists because DNA is antiparallel and replication always occurs in the 5' to 3' direction.
What is the main reason for there being both a leading and a lagging strand during DNA replication quizlet?Why are Leading and Lagging strands created during DNA Replication? They are created because new DNA can be synthesized only in a 5'->3' direction. The template of the DNA is therefore always 3'-5'.
What do leading and lagging strands have in common?Similarities Between Leading and Lagging Strand
They are classified based on the pattern of replication. However, the leading and the lagging strand are complementary to each other. Furthermore, both strands are made up of DNA nucleotides, which link to each other through phosphodiester bonds.
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